The hypothesis that #platelets foster plaque pathology was recently tested using #transgenic mice. The study is the first of its kind to provide evidence of the #pathological changes in amyloid-beta #plaque size and deposition driven by platelets. https
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"In contrast to the popular hypothesis that platelets foster plaque pathology, our data suggest that platelets might limit plaque growth and attenuate plaque-related neuritic dystrophy at advanced stages of amyloid plaque pathology in APP-PS1 female mice"
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Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice https://t.co/D4cHyl3d43 https://t.co/MgAyPEs2Te
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Immune-mediated #platelet depletion augments #Alzheimer'sdisease in mice: Study https://t.co/MDslkhOZEp https://t.co/TquVbXzv7O