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Clearance of p16Ink4a+ cells: Limited effects on β-cell mass and proliferation in mice https://t.co/7dwjG4Wblz https://t.co/QI86RNXu8f
Clearance of p16Ink4a+ cells: Limited effects on β-cell mass and proliferation in mice https://t.co/7dwjG4Wblz https://t.co/QI86RNXu8f
It is likely that the promoter used to generate these mice does not express in beta cells. Otherwise all beta cells past 4 months express p16 and should all be removed. Likely effect due to removal of senescent in other tissues such as adipose. https://t.c
Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity https://t.co/GSHKUujdVA @AgingJrnl https://t.co/SVHvTlDCeF